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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e95732143e7e19fdfcb9da37d606c11ca50b1dea39670cece4f433db7009586d' 
  AND token = 'H+H+UwmsdzFLJ8IoHZ7v/oc3H44NK70Sm10WW7mQlBs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}