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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04f1e443b954f54088383edffe8f6af09b4e93c48fb2643cb18e71e21bbccd16' 
  AND token = 'yD7R3DFXvvrdgrra7rlnyUQXtJ7/6SYSg63xjd15mRI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}