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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f66cb90a73b6187e2694d6494c8508e79c64b8eb8cff59b3d597a7b6bfbb1578' 
  AND token = 'uFZgdu819Iwi2g/rxcOGPhwt/5PcRLh6p5B25DoMYbA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}