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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '053bd1eb9b886ef4351dc8af6474724a0e19f4de11b1f1a289d3102649688f31' 
  AND token = '527EtMbx/KnbUWyXTX/+Y942iJi49pEhsi1k/VVj69A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}