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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d3ca7f4aea99911c576b073c70b60a6dbb7ef3b6bc72b678f570eadf2b4c446' 
  AND token = '73xg/AePdSKfoc8Zk8HD4xanGHkje4x6DGqO7uGF91c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}