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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edad552dd6b879fd7314ad78848a3250788357b76cf0e3c47299bd8ef08c2991' 
  AND token = 'baOBVl7qWem1vgDBaYYsBe82TkZUQu4WMBM48BVCWXo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}