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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9511db3123f5621c92e2a2a9a4c1bc5c3a48c7bbe8063edb12064766b535e2a9' 
  AND token = 'XtciUhoOK9WGBZlpD7uWOEkAOvkAwNgCPv7ZbcuwmOg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}