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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46dc5ec3e42c99004f1b1d916011e39d70339a2d1477a806775931721cd4f9ab' 
  AND token = 'X5CPfbq+Qn/Ekjs/iHK/62EMSfYO3c1cCzWdqvEhcLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}