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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4ba4604d22cbc1514dc8f5d88602e54a51880e69a71eb1a7482e2948186d401' 
  AND token = 'TQbBMCdQYLDWOz1n2zlcR9Noo9EhiYaJ/aVr+y5jHq0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}