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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69855cff04f1235c85b4af0cd0f99cac5cb31566f0563fd93a4afaf2b5b1edd4' 
  AND token = 'zj0NcUZ4IKx2QvQg+EjUU+8b4cq7+8TcEDXCYOrx0sU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}