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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fa8f1a2d28c3576fd3507d4ca721bfb7f884247be18e9f7d9f370f83a32e242' 
  AND token = 'H3QMU2pup1/cqf4fgHr+RVeyas5Ab48YrVKqnoffUZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}