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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99585ed2a7be83b12e1009081de39fc90be9bef30da4fcf80c5de139326cfcf4' 
  AND token = 'VoC1VaHJkcjKrrOAGWOVun1AFydYsWyVkqs+BN1vI2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}