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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '380fa3d092e663918dacca6a916d2e319acf813eb4e469aac53be6a9e0fa1474' 
  AND token = 'e54q2ayqvPhX+C+bqaetMjkcg0yPMbOlMsIIb2y13Qs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}