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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c541329568aa6c89b62a0283eda7373f0a47505e19d710a7c40e63e512e671ca' 
  AND token = 'tUmzTxsxmQb1EdwubQG5sqa2YNDqg8y54WFTp1ddzfM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}