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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8e9ced37d5ce9724e5fb098bd6f2e04d9af16cda6977c1449c216a4902e8bf8' 
  AND token = 'W5Fn0Z957fKqF67UTWPpwm0oaxsTM2kAv1BYpcGzqXM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}