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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac406c681a6c0c932f7594ead993a1a78f5185fe7bebbb5f988dc7a025678b34' 
  AND token = 'H5oSlqDkR7t92UPI7FIkuaY+PQAuN2/XCR7/MUC/YrY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}