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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '134748948d9e8cce2ab32178a9819f5d5aac03f90c7b3e6da80ac37d96ee8514' 
  AND token = 'IuP72+l800tEX/wuKMJomzj8H/+eJUAXFE0rXrIe1/g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}