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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '580c7d481ac2aa04ab3e9e6d7205d829db0de185d3ff05bb85ab81c79f28a103' 
  AND token = 's8skoPSm26uc1tQjZV8I0pjuhA34hkkDb50vyGLrKRg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}