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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e7a5e474e7f147d0289e2fa7ad69ff3ebaa358721b7db166d7d2038e62c6109' 
  AND token = '4bEePYVArnXZFqQ45Re8E4/4efLW50t6jHeGeXTWIAw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}