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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b46425feddb1bec7c5dec89576a5e11670f235535fe281d68b81406c4d821d04' 
  AND token = '2cZr/rmHfsClrSoSrf0aUM28+5ysOnBPl2om3d26NDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}