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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '149ede0ce89cac15a8526d7ad4daeebecf4eea4a502d3248ae9bd80922c62014' 
  AND token = 'ALE1EZ7Ke7UlEm7Svoadv790grukrkZiMLyMxLtaNmc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}