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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54977824783b5e518b05cf478975e0a250e89f9d1df76112d8454cb24fe7d84c' 
  AND token = '4SzuvUPDeUHK5+n9N1XShmsoIa0rbJOF/u1poA//sS0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}