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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39b7cfb33486cf705ed5cfd4c858ee319dd35b4e28e5fa51b04879d3ed909cbe' 
  AND token = 'G0ejZyCon8yTiiC8a6YyLcQcV3y6nlLRMbOYbhUASpM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}