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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86bb2252923baf2029b0aa874115722e4b87fd9d04e6f8f9f03ca4c38310bf36' 
  AND token = '2pxNZMzKYV7o4RGwo6buJUFPtEym3oi65FwC/2XX0S8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}