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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09c45589eb1d41ce0d88c92c7dd142b700ff8adfd1204b4476f088a9e69ec20f' 
  AND token = 'FKys2aj9Ggv+2bfseKf3Tu0HD1UDmbTc+VHFWRF8iOc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}