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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f16fdd7a1d7f83e7c2d1513e46315e50276fd35fa74f29b07cb7a7478edc3570' 
  AND token = 'e8hUXiS/bQ0jFFbNS6041sNLMoUtEuOdqgV49t7ykEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}