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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16e6f6df898c31e96a98611f41e3902e5b670301700f2c7c5f5d3605352d0d7c' 
  AND token = 'KLIsoAFWYgzS6PeAM2DgxaCUaAZD9MxTbDpL5SENl68=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}