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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7e788cfd9c80f785596520a22ca9af3aaec4f55c0952e1d2dcf46be145af516' 
  AND token = 'xiJteVJwAeizVjvm91+uSQcSItgykeXWQELplXBBeBI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}