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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a615647a009b38cc30be3fcc7434ac1f57ac84d268b5e2207b8a027a78af4379' 
  AND token = 'F/iYF4Hq80AC4q0KBLsjDrI5+0j5Ui6bv16bGFkIfL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}