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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '13414a82d1913ab17f0a7b953d4b186de1104a7e24f2fa55b1112738083d850c' 
  AND token = 'RYR5R89ePNPl5Y42RQzyX4LFfGqMBUF/Tr1xNdW5MFA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}