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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae4a668a4f8fdfb4fb1f0c04b166a2b647a740423777b5f0359130a8dc3d6c02' 
  AND token = 'P1ZXRQL97nnt0jx9ecrrwUBsAw5/oWXkpvFyxud/o04=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}