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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b5e310dd1f672b112d2850b260805b26dc659a40dd74aa221b8332e35f6e6be' 
  AND token = 'SWytxPZpb3YN67McW0aC75r3w2EZN3D45nRQgMo2Pdc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}