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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e0bc1af613b38e0568d49b32c0cdc9c1a41a269bc9812d55d75acde97f6fc2e' 
  AND token = 'n9I3tDAJMMODgPS+XgcDoZqHp6eollht7WjF0AGCB2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}