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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ee417427ad3aacfd6324ef973eec26ca353c1f1db1da839ffa8f1e76db26ead' 
  AND token = 'brFUG0s+Q8y5MM1Q7a1f4YphcRLEePGaLqU4jqpasaY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}