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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8730de1fed3ffe17cd6e3a7450bd5783a5e9c17c453b6a50cf5e66800e64aaf3' 
  AND token = '4U1b2hhdMfd/pQd+4iy3F7Fc0w14iXcs5XEzoBSbADo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}