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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '467c3243a74ea0e95c76059b0dbb9714be402b19e36a1e5bbd7ef47111bf2093' 
  AND token = 'UZRdKmoeK52FflXfaAWN6773YeEQ9/RT3cbZtRKtGb8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}