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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1bea34bef8231b7746f5c656a3ba60b2f4f28bc7ee720e057eb11f1b46180ecc' 
  AND token = 'AnrWMMOy4DqXwJVtPhxR8wBX06OuTmzPD60y6+qcpmA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}