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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7657bbcf4d935ad41f57c1dd96795df449734a2af8a0e3ff8272e00cc7a29ac4' 
  AND token = 'QpqWAUMU4pJ3GwMFqneeMZMTQStGsaBiyP+05Vy8y/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}