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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72b365476a09f09287299b53149eebe0919df9762f563488d8dd75917270f1dd' 
  AND token = 'v8/ZDiXmvMwxiihyFt6uS+qP7AEeuXIxMfECYAMaUV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}