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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '304fe1521bbf3d39490c20f4fd7f1b24b19233ee8a0a1f276323933b8aee4af4' 
  AND token = 'RxqR95zEFZs12SIDn/ezEhrc/jj4DgyiUwYFsU2EeYc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}