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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '733424deb2d5f29c5a7eca5301e7bff06ce58f701165e336f52d257a2b70442c' 
  AND token = '4Nm3G6/95WLW/DOowAp4s8mruOCIW+pDyQ6Bq7nFo6Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}