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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef13ce80cd7f5e45a7510ca048a81ad89631ebe264e381167a736b2f465edd06' 
  AND token = 'oXMITKGB1BHrPIXG9LvhZty3fopSm4yetyGUX9PqSR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}