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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd825a1f0093c06e2a732fa1bbde0fa9c338a2e02059830cdd34198ca3dd0718b' 
  AND token = 'UmEdAVFsHhtDkY2/fEk9GdyttqnJCdKHNVLLH9/9Ngs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}