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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a4ceab4e328d21d03e775e8233d48a7aacf7e4e23df2888e65a975d6c9ebdcd' 
  AND token = 'EZIu05Coy6Uq/PQvEGDhYP0imFbn/e3AqQ0N0oVhkd0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}