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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0246930e0d4f583dd3a5e2a940b8727083552540b0e88effed6db818b7ea99dc' 
  AND token = 'HxLQ8fm3p9/ziRHuO5sldCsAMfoeOhtQDUUO2UB4LMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}