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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6c67c76fb6fd353177963aaa2941b7f952bdd49f1340d2b760c0fbc0a0d013c' 
  AND token = 'XN+yCl4V+ThbN09ZYO146kspt7qJmh2VMsCrzvEdXhU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}