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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21061b2e917cd3c773c02a21bfb2d14993b8183ae3c8f694b0093700933aa1ce' 
  AND token = 'SEar8JB+lTFKNngToW7iWybJfYF5/ArbIo2kqqTNdjU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}