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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '379d0bfc19c3a79bb94a227578f4328b5de6ce4394a7f39b10d64202b5a0276e' 
  AND token = 'dmjV1r9GJHunoPm/1C7mCb5Jo9xZNbdUUeqaB48VFA8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}