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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b87345f35d2aae1a67ff1003b8d50893049792fe213b9a5c6aebf4c5b808d69a' 
  AND token = 'EQ7s5V4qCeUbM4F6swSvhUq8t8Tvx7Ch6IjhtVCQbnc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}