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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9003841e47025018ead3d9573255cf71c647c162c18bf0946a02a54f2364e508' 
  AND token = 'm+Iois5+KpyoKKMfAoyAzVYhKk1ZGISy5weU1KGrpc8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}